Comprehensive Cone-Beam Computed Tomographic Findings in Gorlin–Goltz Syndrome: A Case Report

Abstract

Gorlin–Goltz syndrome (GGS), sometimes called nevoid basal cell carcinoma syndrome, is a rare genetic condition inherited in an autosomal dominant manner, most often resulting from changes in the PTCH1 tumour suppressor gene. It affects multiple body systems, with common features including jaw cysts (odontogenic keratocysts), skeletal abnormalities, and calcifications within the brain. Here, we describe an unusual case of GGS in a 24-year-old woman who came to us with a painless swelling in her jaw. Cone-beam computed tomography (CBCT) scans revealed several jaw cysts and a distinctive calcification of the falx cerebri, which met key diagnostic criteria for the syndrome. This case highlights how valuable CBCT and the expertise of dental professionals are for the timely detection and comprehensive care of individuals with Gorlin–Goltz syndrome.